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Institute of Neuroscience, NYMU
Category
Yung-Yang Lin Professor

Education:

M.D., Taipei Medical University School of Medicine, Taipei, Taiwan; Ph.D., National Yang-Ming University, Taipei, Taiwan

Resident (Neurology), Taipei Veterans General Hospital, Taiwan

 

Current academic appointments:

Director, Cerebrovascular Disease Section, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan

Consultant Neurologist, Taipei Veterans General Hospital, Taipei, Taiwan

Director, Laboratory of Neurophysiology, Taipei Veterans General Hospital, Taipei, Taiwan

Professor, National Yang-Ming University School of Medicine, Taipei, Taiwan (Institute of Brain Science, Institute of Physiology, and Department of Neurology)

Executive Board Member, Taiwan Stroke Society, Taiwan

Executive Board Member, Taiwan Neurological Society, Taiwan

Executive Board Member, Taiwan Epilepsy Society, Taiwan

Executive Board Member, the Taiwan Society of Clinical Neurophysiology, Taipei, Taiwan

 

Professional history, affiliations, honors, and research interest

Dr. Lin is an Attending Physician of Neurology (1994-present) and Principal investigator at the Department of Medical Research and Education (2002-present) at the Taipei Veterans General Hospital in Taiwan. He was an Assistant Professor (1999-2003), Associate Professor (2003-2006), and is now a professor (2006-present) at National Yang-Ming University School of Medicine in Taiwan. He was a visiting scientist at the MEG lab of Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology in Finland from 1999 to 2000. He was also the President of the Taiwan Society of Clinical Neurophysiology in Taipei, Taiwan from 2010 to 2013. He was awarded the Excellent Teaching award by Yang-Ming University in 2016, the GSK Epilepsy Research Award of Taiwan Epilepsy Society in 2015, the Annual Research Award by the Taipei Veterans General Hospital in 2012, the Research Award of LiFu Medical Research Foundation in 2012, the Excellent Teaching Award by Yang-Ming University in 2010, the Medical Treatment Technology Innovation Award by Taipei Veterans General Hospital in 2005, and the Annual Research Award by Taiwan Neurology Society in 2004. He has published 119 papers in the field of stroke, epilepsy, and dementia.

 

AWARDS AND HONORS:

2016: Excellent Teaching Award, Yang-Ming University, Taiwan

2015: GSK Epilepsy Research Award of Taiwan Epilepsy Society

2012: Annual Research Award, Taipei Veterans General Hospital, Taiwan

2012:Research Award of LiFu Medical Research Foundation, Taiwan

2010: Excellent Teaching Award, Yang-Ming University, Taiwan

2005: Medical Treatment Technology Innovation Award, Taipei Veterans General Hospital, Taiwan

2004: Annual Research Award, Taiwan Neurology Society, Taiwan

 

CURRENT RESEARCH:

Ministry of Science and Research: Effects of soluble epoxide hydrolase activity on microgliapolarization in white matter and ischemic penumbral cortex after experimental stroke

Ministry of Science and Research: Assessment of the effects of low-intensity pulsed ultrasound on brain white matter inflammation in ischemic stroke

Taipei Veteran General Hospital: Clinical role of ultrasound in acute ischemic stroke of patients with atrial fibrillation

 

RESEARCH DIRECTION:

Specialty: Clinical neurology

Stroke/ cerebrovascular events

 

RESEARCH INTEREST: 
1. Ischemic stroke research

2. The relationship between microglia polarization and ischemia

 

FUTURE DIRECTION:

1. Investigate the roles of microglia in white matter injury in ischemic animal model

2. The interaction between microglia and oligodendrocytes in ischemic animal model

3. Finding predictors of clinical outcome in acute ischemic stroke patients


Publications

(selected publications in recent 3 years1-23):

  1. Liu HY, Chou KH, Lee PL, Fuh JL, Niddam, DM, Lai KL, Hsiao FJ, Lin YY, Chen WT*, Wang SJ*, Lin CP. Hippocampus and amygdala volume in relation to migraine frequency and prognosis. Cephalalgia 2016 (IN PRESS) (SCI) (I F= 6.052;R/C= 13/193,CLINICAL NEUROLOGY )
  2. Hung YW and Lin YY*.Targeting soluble epoxide hydrolase for temporal lobe epilepsy. Journal of Clinical & Experimental Neuroimmunology 2016 Volume (1) 2- 1000101
  3. CL Kuo, AS Shiao, SJ Wang, WP Chang*, YY Lin*.Risk of Sudden Sensorineural Hearing Loss in Stroke Patients: A 5-year Nationwide Investigation of 44,460 Patients. Medicine (Baltimore). 2016 Sep;95(36):e4841. (SCI) (I F= 2.133;R/C= 40/155,MEDICINE, GENERAL & INTERNAL )
  4. KH Chou, FC Yang, JL Fuh, CY Kuo, YH Wang, JF Lirng, YY Lin, SJ Wang*, CP Lin*. Bout-associated intrinsic functional network changes in cluster headache: a longitudinal resting-state functional MRI study. Cephalalgia 2016 Sep 7. pii: 03331024 (SCI) (I F= 6.052;R/C= 13/192,CLINICAL NEUROLOGY )
  5. FJ Hsiao, WY Hsu, WT Chen, RS Chen, YY Lin*. Abnormal Somatosensory Synchronization in Patients with Paroxysmal Kinesigenic Dyskinesia: an MEG study. Clinical EEG & Neuroscience 2016 DOI: 10.1177/1550059416662575 (SCI) (I F= 1.862;R/C= 120/192,CLINICAL NEUROLOGY )
  6. CH Cheng, YJ Tseng, RS Chen, YY Lin*.Reduced functional connectivity of somatosensory network in writer's cramp patients. Brain and Behavior 2016 Jan 26:e00433 (SCI) (I F= 2.243;R/C= 30/51,BEHAVIORAL SCIENCES )
  7. CH Cheng*, Sylvain Bailleti, YY Lin. Region-specific reduction of auditory sensory gating in older adults. Brain and Cognition 2015 Dec;101:64-72. doi: 10.1016 (SCI) (I F= 2.477;R/C= 154/252,NEUROSCIENCES )
  8. PY Huang, YH Shih, YJ Tseng, TL Ko, YS Fu*, YY Lin*.Xenograft of Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly as a Potential Therapy for the Rat Pilocarpine-Induced Epilepsy. Brain, Behavior, and Immunity 2015 Dec 28. pii: S0889-1591(15)30083-0 (SCI) (I F= 5.889;R/C= 20/148,IMMUNOLOGY )
  9. CH Cheng, CJ Liu, SM Ou, CM Yeh, TJ Chen, YY Lin*, SJ Wang*. Incidence and risk of seizures in Alzheimer's disease: A nationwide population-based cohort study. Epilepsy Research 2015 Sep;115:63-6(SCI) (I F= 2.190;R/C= 96/194,CLINICAL NEUROLOGY )
  10. WY Hsu, Theodore P. Zanto, Joaquin A. Anguera, YY Lin, Adam Gazzaley*. Delayed enhancement of multitasking performance: Effects of anodal transcranial direct current stimulation on the prefrontal cortex. CORTEX 2015 May 22;69:175-185(SCI) ( I F= 6.042;R/C= 4/49,BEHAVIORAL SCIENCES )
  11. HY Liu, JL Fuh, YY Lin, WT Chen *, SJ Wang*.Suicide risk in patients with migraine and comorbid fibromyalgia. Neurology 2015 Sep 22;85(12):1017-23 (SCI) ( I F=8.303;R/C= 8/194,CLINICAL NEUROLOGY ) 
  12. FJ Hsiao*, HY Yu, WT Chen , SY Kwan, C. Chen, DJ Yen, CH Y, YH Shih, YY Lin*.Increased Intrinsic Connectivity of the Default Mode Network in Temporal Lobe Epilepsy: Evidence from Resting-State MEG Recordings. PLOS ONE 2015,10(6): e0128787 (SCI) ( I F= 3.534;R/C= 8/55,MULTIDISCIPLINARY SCIENCES )
  13. CH Cheng*, PY S Chan, Sylvain Baillet and YY Lin*. Age-related reduced somatosensory gating is associated with altered alpha frequency desynchronization. Neural Plasticity 2015. Article ID 302878 ( I F= 3.608;R/C= 88/252,NEUROSCIENCES)
  14. WY Hsu, YF Kuo, KK Liao, HY Yu, and YY Lin*. Widespread inter-ictal excitability changes in patients with temporal lobe epilepsy: A TMS/MEG study. Epilepsy Research 2015 Mar;111:61-71 (SCI) ( I F= 2.190;R/C= 96/194,CLINICAL NEUROLOGY)
  15. CH Cheng, Sylvain Baillet, FJ Hsiao, and YY Lin* .Effects of aging on the neuromagnetic mismatch detection to speech sounds. Biological Psychology 2015(104) 48-55 (SCI) ( I F= 3.473;R/C= 16/74,PHYSIOLOGY )
  16. FJ Hsiao*, FY Hsieh, WT Chen, DC Chu, YY Lin*. Altered Resting State Cortical EEG Oscillations in Patients with Severe Asymptomatic Carotid Stenosis. Clinical EEG & Neuroscience 2014 DOI: 10.1177 /1550059414560396 (SCI) ( I F= 3.157;R/C= 54/194,CLINICAL NEUROLOGY )
  17. KH Chou, FC Yang, JL Fuh,CC Huang, JF Lirng, YY Lin,PL Lee, HW Kao, CP Lin and SJ Wan. Altered white matter microstructural connectivity in cluster headaches: A longitudinal diffusion tensor imaging study.Cephalalgia 2014 V34(13) 1040-1052 (SCI) ( I F= 4.121;R/C= 32/194,CLINICAL NEUROLOGY)
  18. YW Hung, SW Hung, YC Wu, LK Wong, MT Lai, TS Lee*,YH Shih and YY Lin*.Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain, Behavior, and Immunity 2014 Aug 15 (14)00408-5 (SCI) ( I F= 6.128;R/C= 19/144,IMMUNOLOGY )
  19. FJ Hsiao*, WT Chen, PN Wang, CH Chen,and YY Lin*.Temporo-frontal functional connectivity during auditory change detection is altered in Alzheimer's disease. Human Brain Mapping 2014 ;35(11):5565-77. (SCI) ( I F= 6.924;R/C=2/122,RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING )
  20. FC Yang, KH Chou, JL Fuh, PL Lee,JF Lirng, YY Lin, CP Lin, SJ Wang* .Altered hypothalamic functional connectivity in cluster headache: a longitudinal resting-state functional MRI study. Journal of Neurology, Neurosurgery, and Psychiatry 2014 June jnnp-2014-308122 (SCI) ( I F= 5.580;R/C= 15/194,CLINICAL NEUROLOGY )
  21. YJ Tseng, RS Chen, WY Hsu, FJ Hsiao, YY Lin*.Reduced Motor Cortex Deactivation in Individuals Who Suffer from Writer's Cramp. PLOS ONE 2014 15;9(5):e97561. (SCI) ( I F= 3.534;R/C= 8/55,MULTIDISCIPLINARY SCIENCES )
  22. CH Cheng, BW Soong, WY Hsu and YY Lin*.Reduced automatic frontal response to auditory deviance in Huntington's disease as indexed by magnetic mismatch negativity. Journal of Clinical Neuroscience 2014 Oct;21(10):1773-8 (SCI) ( IF= 1.318;R/C= 151/194,CLINICAL NEUROLOGY )
  23. FJ Hsiao*, WT Chen, YJ Wang, SH Yan, YY Lin*. Altered Source-based EEG Coherence of Resting-State Sensorimotor Network in Early-Stage Alzheimer's Disease Compared to Mild Cognitive Impairment. Neuroscience Letters 2014 Jan 13;558:47-52. (SCI) ( I F= 2.055;R/C= 178/252,NEUROSCIENCES ).
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